Wellcome Sanger Institute

Wellcome Sanger Institute

The Wellcome Sanger Institute is one of the premier centres of genomic discovery and understanding in the world. It leads ambitious collaborations across the globe to provide the foundations for further research and transformative healthcare innovations.

Telephone: +44 (0)1223 834 244
Address: Wellcome Genome Campus, Hinxton
Postcode: CB10 1SA
Country: United Kingdom
Website: http://www.sanger.ac.uk
Membership type:Corporate 51+ (£1,000+VAT pa)

Its success is founded on the expertise and knowledge of its people and the Institute seeks to share its discoveries and techniques with the next generation of genomics scientists and researchers worldwide.

Annie Cavanagh, Wellcome Images and Photoroyalty, freepik.com

Major mutation pattern in cancer occurs in bursts

Researchers have created a huge resource for investigating the biological mechanisms that cause cancer. The scientists from the Wellcome Sanger Institute and their collaborators identified which patterns of DNA damage - mutational fingerprints that represent the origins of cancer - were present in over a thousand human cancer cell lines.

11 March 2019Read in full

WHO Technical Note global surveillance of AMR

Improving global surveillance of antibiotic resistance

A World Health Organization (WHO) Technical Note has been published that will enable health authorities to make informed choices on the most appropriate molecular tests in order to achieve a clearer picture of antimicrobial resistance globally.

28 February 2019Read in full

Horse and dog

Cancer comparison across species highlights new drug targets

Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time by scientists at the Wellcome Sanger Institute and their collaborators. Researchers sequenced the genomes of the same cancer across different species to pin-point key cancer genes.

13 February 2019Read in full


100 cancer organoid models developed by Sanger Institute scientists

Researchers at the Wellcome Sanger Institute have developed 100 cancer organoids.The work was co-funded by Cancer Research UK and the Sanger Institute and leads the UK effort as part of the international Human Cancer Model Initiative (HCMI). The organoids will soon be available for researchers, together with associated data including whole genome sequences.

6 February 2019Read in full

New gut bacteria discovered in human microbiome

More than 100 new gut bacteria discovered in human microbiome

Scientists working on the gut microbiome* have discovered and isolated more than 100 completely new species of bacteria from healthy people’s intestines.

5 February 2019Read in full

The human whipworm - Trichuris trichiura

Immune master regulator orchestrates responses to parasite infection

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms. Researchers from the Wellcome Sanger Institute and collaborators have revealed that the interleukin 10 receptor (IL-10R) is critical to prevent uncontrolled whipworm infection in mice and a damaging immune response in the gut.

1 February 2019Read in full

Baby in womb / Dr Wolfgang Moroder, Wikimedia

Genetic testing gives answers on developmental disorders during pregnancy

Genetic testing improves the diagnoses of abnormalities in developing babies that are picked up during ultrasound scans, scientists report in The Lancet.

1 February 2019Read in full

Mosquito. Image credit: James Gathany, CDC PHIL

Scientists take huge step forward in decoding genomes of small species

For the first time, scientists have read the whole genetic code of one single tiny mosquito.

30 January 2019Read in full

Replacement of the left hip joint

Genetic study reveals possible new routes to treating osteoarthritis

In the largest genetic study of osteoarthritis to date, scientists have uncovered 52 new genetic changes linked to the disease, which doubles the number of genetic regions associated with the disabling condition.

24 January 2019Read in full

T helper cells / Image credit: NIAID

CRISPR study reveals new immune system regulators

Scientists have created the first retroviral CRISPR-Cas9 gene editing library to explore the regulation of mouse T cells, which are key cells in the immune system. Researchers from the Wellcome Sanger Institute and their collaborators have mapped the most important genes for controlling T helper cells, and identified several new potential regulatory genes.

11 January 2019Read in full

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