MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

The MRC Laboratory of Molecular Biology (LMB) is a world-class research laboratory, dedicated to understanding important biological processes at the molecular level – with the goal of using this knowledge to tackle major problems in human health and disease.

Telephone: +44 (0)1223 267 000
Address: Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge
Postcode: CB2 0QH
Country: United Kingdom
Website: http://www2.mrc-lmb.cam.ac.uk/
Membership type:Cambridge University Department

The LMB is one of the birthplaces of modern molecular biology. Many techniques were pioneered at the laboratory, including DNA sequencing, methods for determining the three-dimensional structure of proteins and the development of monoclonal antibodies.

Over the years, the work of LMB scientists has attracted twelve Nobel prizes, dozens of Royal Society awards and numerous other scientific honours.

In addition, many of our scientists have succeeded in exploiting their discoveries through technology transfer generating over £700 million of commercial income, to help support UK science.

Benjamin Falcon

MRC researcher receives the 2019 Alzheimer’s Research UK Rising Star Award

Benjamin Falcon, a postdoctoral researcher in Michel Goedert’s group in the MRC Laboratory of Molecular Biology's (LMB’s) Neurobiology Division, has been awarded the inaugural Alzheimer’s Research UK Rising Star Award in recognition of his significant contribution to biomedical dementia research as an early career researcher.

22 March 2019Read in full

New system can identify drugs to target ‘undruggable’ enzymes critical in many diseases

New system can identify drugs to target ‘undruggable’ enzymes critical in many diseases

A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly “undruggable”.

27 July 2018Read in full

Greg Jefferis awarded Francis Crick Medal and Lecture by the Royal Society

Greg Jefferis awarded Francis Crick Medal and Lecture by the Royal Society

Greg Jefferis, group leader in the LMB’s Neurobiology Division, has been awarded the Francis Crick Medal and Lecture 2018 in recognition of his discoveries concerning the developmental and functional logic of sensory information processing.

19 July 2018Read in full

Dr Richard Henderson

Queen's Birthday Honour for MRC scientist

Dr Richard Henderson, Molecular Biologist and Biophysicist at the MRC Laboratory of Molecular Biology (LMB), was made a Companion of Honour in the 2018 Queen’s Birthday Honours for services to electron microscopy of biological molecules.

12 June 2018Read in full

Michel Goedert is awarded The Brain Prize 2018

Michel Goedert is awarded The Brain Prize 2018

Michel Goedert from the LMB’s Neurobiology Division has been awarded the 2018 Brain Prize. Michel shares the award with fellow neuroscientists Bart De Strooper, Christian Haass and John Hardy “for their groundbreaking research on the genetic and molecular basis of Alzheimer’s disease”.

6 March 2018Read in full

Credit: Dean Clift / MRC LMB.

New technique ‘Trim-Away’ targets and rapidly destroys proteins in cells

A new technique, called ‘Trim-Away’, directly and quickly depletes proteins from any cell type in culture. As Trim-Away can also distinguish between different variants of the same protein, it opens up new opportunities to understand the role of proteins in disease, say the scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) in Cambridge and the Max Planck Institute (MPI) for Biophysical Chemistry in Germany.

20 November 2017Read in full

Richard Henderson wins 2017 Nobel Prize for Chemistry

Richard Henderson wins 2017 Nobel Prize for Chemistry

Richard Henderson from the LMB’s Structural Studies Division has been awarded the 2017 Nobel Prize for Chemistry. Richard shares the honour jointly with Jacques Dubochet and Joachim Frank “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution”.

4 October 2017Read in full