This one day course covers, step-by-step, the way in which discovery projects are systematically moved from initial ideas through the several stages required to generate potential drugs worthy of entering the clinic. Typical attendees include science-based professionals: biologists, molecular biologists, chemists, preclinical development scientists, informaticians, patent attorneys, project managers and general managers.
Objectives:
The course is a ‘one-stop-shop’ outlining the major scientific tools of drug discovery, namely: Drug Discovery Biology, ADMET/PK/PD, Medicinal Chemistry, Informatics/Virtual technologies and how these contributions are phased over time and integrated to generate a drug suitable for clinical trials.
The focus is on small molecule drugs with comparisons made with biologics. Based on real-world experience and practical realities, attendees travel step-bystep along the typical path.
Initiating Idea -> Drug Target Protein Selection -> Lead Identification -> Clinical Candidate Nomination. Essential related topics including: Drug discovery technology platforms Drug structural and functional quality attributes. Project management tools-Target Product Profile (TPP) use.
Key technology and infrastructure requirements are also covered in the course.
