Opportunities for permanent roles in a range of business sectors

Research Associate: Gene expression

4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapy and gene editing platforms. We are expanding our research and development team at our site near Cambridge, UK to facilitate the scaling of our proprietary DNA manufacturing process, develop vectors for DNA delivery and explore gene editing strategies for therapeutic indications. We are looking for dynamic and experienced team members to help us achieve our ambitions and goals.

We are now recruiting for an experience Rearch Associate: Gene expression


  • Work independently to develop and optimise systems to enhance gene expression for in-house projects
  • Confidently plan, execute, and deliver projects to a high standard and in accordance with project plans
  • Analyse and interpret experimental data; identify and solve experimental problems
  • Drive the evaluation and optimisation of novel gene expression systems
  • Work with mammalian cell cultures, and use non-viral vectors for in vitro delivery
  • Work collaboratively and support the R&D functions of the Company
  • Attend and participate in relevant meetings, training, and development sessions
  • Use and maintain company equipment in accordance with the company’s SOPs and health & safety guidelines
  • Undertake any other appropriate roles and responsibilities that reasonably fall within the role holder’s skills and experience as requested
  • Be prepared to travel to other 4basebio sites
  • Keep up to date with relevant scientific and technical developments

Essential requirements:

  • PhD or demonstrable equivalent experience in biological sciences, with significant experience in molecular biology
  • Extensive knowledge and practical experience in construct design and DNA cloning
  • Experience with IVT RNA desirable
  • Experience in mammalian cell culture, preferably primary cells
  • Ability to test and troubleshoot new assays and techniques
  • Excellent team working and communication skills

What we offer:
Competitive salary + private healthcare + pension contributions + life assurance

We can only consider candidates who hold the right to work in the UK

To apply for this role, please submit your CV and covering letter