Assay Scientist, Biologics Engineering, Oncology R&D

AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

As an Assay Scientist, you will be responsible for providing critical biochemical and cell assay expertise to deliver multiple biologics drug discovery and technology development projects using state of the art technologies. This is a lab-based role involving independent design, execution and interpretation of scientific experiments, and effective communication of findings and recommendations as part of a multi-disciplinary project team. You will also contribute to the identification and development of cutting-edge technologies that benefit biologics drug discovery and have a proven track record of creatively solving scientific challenges.

About AstraZeneca

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

Site description

This role will be located on the Cambridge Biomedical Campus, this site combines biomedical research, patient care and education on a single site location in the heart of Cambridge. The office will be within walking distance of the new purpose-built building that will bring together the company’s research and development activity in a state-of-the-art strategic R&D centre and global corporate headquarters. The building has been crafted with the open architecture reflecting AstraZeneca’s approach to research. Open laboratories and glass walls will enable new ways of working across teams, whilst a central courtyard will put science on full display.

Business Unit

The Biologics Engineering team is responsible for the discovery and optimisation of biological candidate drugs across multiple therapy area drug discovery pipelines. The team also leads the development of in-house biologics discovery platforms and novel drug modalities to support future drug discovery efforts.

What you'll do

  • Development of biochemical and cell based 96 or 384 well binding and functional assays for use as biologics screens and pharmacological characterisation of biologics for drug discovery or technology development projects, delivering work on time and to budget

  • Contribution of expertise to multi-disciplinary research drug discovery and technology projects, effectively communicating recommendations and contributing to team decisions

  • Identification and development of new screening and automation technologies and processes

  • Maintaining a well-developed understanding of approaches to biologics drug discovery and applying a broader functional knowledge to support the department

  • Identification of creative solutions to assay, technology or drug discovery project problems

  • Contributing to peer reviewed publications, patents and participating at international conferences

  • Providing technical training to members of the team where required

  • Ensuring own work, and work of peers, is compliant with General Laboratory Standard, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations


Essential skills

  • Bachelor’s degree in a relevant field

  • Experience and technical knowledge of biologics assay development, screening and use of automation, with a commitment to quality and scientific rigour

  • Strong team player with good communication skills and experience of working in multi-disciplinary teams

  • Ability to address challenges creatively and a drive to contribute to the development of new and improved assay technologies and processes

Desirable skills

  • Background in drug discovery and development in the pharmaceutical industry

  • Knowledge of biologics drug discovery and in vitro pharmacology

Competitive salary & benefits

Close date: 23/02/2024

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big.

So, what’s next!

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it’s yours.

Where can I find out more?

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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