Are you a Life Scientist with a solid background in in vitro assay development, looking to expand your experience within the pharmaceutical industry? Are you driven by a commitment to help patients and explore the potential of science? We have an exciting opportunity for you at AstraZeneca. Join us on an 18-month fixed term contract as part of the Bioassay, Biosafety and Impurities Group. This team is responsible for developing cutting-edge methods to evaluate product quality, enabling product understanding, manufacturing process development, formulation, drug product development and regulatory filings. We are seeking a dynamic and highly motivated lab-based scientist with proven experience in in vitro biological activity methods.
- Use your knowledge of cell culture and hands-on biological assay development in a team oriented environment
- Support our drug development programmes with data, effectively utilising existing and novel technologies and instrumentation
- Convert opportunities and resources to succeed and thrive around the team and communicate achievements to different audiences, including team meetings, global group meetings and matrix teams.
- Learn from experience and guidelines/documentation to increase responsibilities and complexity of tasks to be performed with a higher level of autonomy.
- Build on AZ’s science driven dynamic environment
Develop biochemical and cell based potency assays based on drug mode of action and carry out routine sample testing in a timely fashion
Enable transfer of any methods to other groups as appropriate
Accurately record all data clearly and concisely with a clear understanding of its implications within the overall context of drug development
Manage own work to ensure that agreed targets are met and to agreed quality standards, communicating progress appropriately.
Discuss and defend experimental findings at cross-functional meetings, representing the Bioassay Team, as well as internal symposia and external conferences.
Prepare for review clear and concise technical documents like SOPs, work plans, work reports and instructional documents
Assist in the training of others in procedures and practices
Ensure that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards
Minimum BSc (or equivalent) in Immunology, Cellular Biochemistry, Cell Biology, Molecular Biology or a related field together with industry experience (up to 6 years relevant post-BSc experience) or PhD with similar academic experience (up to 2 years relevant post-PhD experience)
Thorough understanding of mammalian cell culture and hands-on experience with in vitro cell-based assay techniques and their applications in assessing e.g. cellular signalling, receptor binding and cytotoxicity
Drug development experience in academia, Pharma/Biotech industry
Experience with immunoassay/binding assays
Experience with cell line generation and molecular biology techniques
At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before.
Join us in our Biopharmaceuticals R&D division and be part of a dedicated Research & Development team. Strengthen our pipeline to make a meaningful impact on patients. This is the place to go beyond discovery. We think holistically about patients and are always learning from those living with diseases. We harness digital, data science & AI to fast-forward our research. Making sure work born in a lab can make a real difference. Everyday, impacting patients' lives across the world.
Ready to make an impact? Apply now and join us in pushing the boundaries of science to deliver life-changing medicines!
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.