Director TICA - TME & IO, 14 Month FTC

AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialisation of prescription medicines for some of the world’s most serious diseases. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.  At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations, because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.     

Be part of fulfilling our ambition to be world leaders in Oncology. We are already the fastest growing team within AstraZeneca and across the industry, and there are countless new indications and targets in our game-changing pipeline. The vision of AstraZeneca Oncology is to redefine cancer, redefine our solutions to cancer, and restore patients' lives. To achieve this, we have an exciting and diverse portfolio that focuses on four scientific platforms that we believe show the greatest potential for yielding effective medicines for cancer patients. A place built on courage, curiosity and collaboration – we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline.

We are seeking a Director in Oncology Translational Medicine to join the high achieving Tumour & Immune Cell Atlas (TICA) Translational Team. The TICA team delivers a 360° cancer patient and tumour microenvironment view, correlating multi-omics assessment with clinical SOC for prevalence analysis, novel biomarker identification and survival association. This is a well-established team delivering data to inform clinical trial development, combination strategies, competitor drug comparisons and due diligence for new in-licensing opportunities.  In this role you will be accountable for delivery of robust, scientifically driven biomarkers in drug discovery and development programs.  You will be responsible for co-ordinating and delivering translational science to facilitate clinical evaluation of projects in the portfolio. You will have the opportunity to impact an industry-leading portfolio and provide excellent representation of discovery scientific input to enable successful clinical decisions.

Key Responsibilities and Accountabilities:

  • Tracks and reports on the progress of assigned projects to the appropriate governance, stakeholders and senior management.
  • Collates and tracks budget spend, engaging with key budget stakeholders, as well as contracting and procurement administrative processes.
  • Actively manages and reports project issues and risks, including escalations, as appropriate.
  • Project management support of strategic initiatives that are a business priority.
  • Establishes and leverages best practice processes and systems for project planning and execution that are fit-for-purpose.
  • Coordinates preparation of reports for governance through gathering, analysing, and summarizing data and information from the project teams and systems.
  • Develops key process for delivery of information up to Senior Leaders across R&D.
  • Contributes significantly to the overall strategic direction and development of the TICA team and aligns departmental objectives with the business.

Essential Requirements and Qualifications:

  • PhD and/or MD with extensive experience in drug development.
  • In-depth knowledge of oncology disease area biology and translational science.
  • Demonstrated track record of success in delivering strategic, complex, cross-functional and multi-site projects on-time, on-budget and to committed deliverables to generate significant business value.
  • Takes appropriate initiative and accountability including proactively prioritizing work in alignment with business requirements.
  • Experienced in using MS Office Suite, especially PowerPoint, Word and Excel.
  • Thrive with volatility, uncertainty, complexity, ambiguity (VUCA) in the fast-paced environment.
  • Proven communication and influencing skills.
  • Highly developed problem solving and risk management skills.
  • High level of cultural sensitivity, interactive communication, negotiation and effective collaboration. Considerable tact, discretion and persuasion to obtain desired outcomes while maintaining ongoing professional relationships. Strong interpersonal, collaboration and communications skills

Location: Cambridge, UK

Competitive salary and benefits

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.


So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

  • If you’re curious to know more then please reach out to Sophie Halpin.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Apply now


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