Medical Director OR Senior Medical Director, Early Clinical Development - Rheumatology

AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

Build a long-term career by unlocking opportunities for lifelong learning 

Build unrivalled capabilities in a place that promotes learning agility and offers development opportunities. We never stand still so you’ll have the chance to constantly grow your abilities, skills and knowledge. Here we are a fusion of challenging and interesting work, in an energising and inspiring environment.  

Who we are 

Naturally curious, we are forever connecting and collaborating. Uncovering new insights that equip us to challenge convention and push the boundaries. 

What we do 

We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide.  

How we do it 

Committed to living our values – they guide our behaviours, actions and decisions, everyday. Safe to share and learn from each other – ours is an inclusive environment. Where difference is recognised and uniqueness is valued. 

Are you a passionate Physician who would like to work at the cutting edge of science to develop ground-breaking medicines of the future? As a global, science-led biopharmaceutical company, we in Clinical Development are the beating heart of the business and there’s no better place to work as a physician. 
At AstraZeneca, your innovative contribution will ultimately have the potential to reach millions of patients’ in need across the globe. That is why we love it – this is the place to make a greater impact. Are you ready to join us and see what science can do? 
We are looking to hire a specialty trained Rheumatologist as a Medical Director or Senior Medical Director. Ideally the successful candidate will have several years of Clinical drug Development experience and will join our team within Early Clinical Development, Immunology. 

This role can be based in Cambridge/UK, Gothenburg/Sweden, Barcelona/Spain, Gaithersburg or Boston/US. 
In Early Respiratory & Immunology (Early R&I), we’re driven by innovation and our dedication to make a real-life difference in patients’ lives. That difference starts with you. We are part of the BioPharmaceutical R&D unit. Here, you will get the opportunity to work in a truly international environment and meet and discuss with key opinion leaders, other medical colleagues and authorities in basic science, as well as commercial, regulatory, and other functions to bring new medicines to life. 

What you’ll do: 

As a Rheumatologist and Medical Director/Senior Medical Director at AZ, you would be a key part of the Team working across multiple diseases focused on Rheumatology. 

You will be the single point accountable leader for the design, delivery and interpretation of clinical studies in Early stage (up to Ph3) within AstraZeneca´s global organization. You will be responsible for the scientific & medical strategy as a disease area expert and deliver the Medical Scientific strategies of the Clinical Development Plan to the project team. 

You will operate in a wide range of aspects in pharmaceutical medicine and lead a multitude of contacts within and outside of AstraZeneca such as Senior management team, Regulatory and Finance, Academic partners and CROs. 

You will be familiar with relevant Regulatory guidelines for drug development in the Rheumatological diseases, current treatment guidelines, relevant competitor trial designs and data as these are continually evolving. As such this will enable you to build novel and innovative Early Clinical development plans. 


We rely on you to: 
  • Build positive relationships and networks with internal and external medical community to follow developments within areas of expertise 

  • Design or manage the implementation of the medical strategy within Clinical Development globally 

  • Ensure that clinical input into the Translational Medicine and development strategies and plans receive adequate peer consultation to assure high scientific quality and patient relevance. 

  • Closely follows medical developments within assigned areas and disseminates new information within Clinical Development to transform trends and emerging data into new plans 

  • Act as Medical Lead for regulatory communication and preparation of higher level documents 

  • Ensures internal and external peer review of potential study/programme design 

  • Support qualification of pharmacodynamic/disease markers for early assessment of efficacy 

  • Guide the selection, set up and implementation of key disease assessments, including contributing to the development of novel and innovative endpoints. 


Essential for the role: 

We believe that you are a fully qualified physician (MD or MD PhD) with specialty training in Rheumatology. 

Ideally you will also have several years of pharmaceutical industry experience in clinical drug development, and have significant leadership experience and proven teamwork and collaboration skills. You are also required to travel nationally and internationally. 


You also possess: 
  • Significant experience in the design, monitoring, executing and interpreting clinical trials, with understanding of biomarkers, biostatistics and safety reporting 

  • Excellent interpersonal skills 

  • Fluent verbal and written communication skills in English 


At AstraZeneca, we 're dedicated to being a Great Place to Work, where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development. 


We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. 

So, what’s next? 
Are you already imagining yourself joining us? Good, because we can’t wait to hear from you! 

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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