Pathology Manager in Translational Pathology, Oncology - 12 Month FTC

AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

Pathology Manager in Translational Pathology, Oncology  - 12 Month- FTC

At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe!

We currently have an opportunity for a Pathology Manager to join the Translational Pathology group within the Oncology R&D Cancer Biomarker and Translational Medicine divisions of the company. In this role you will be at the forefront of the evolution of translational science for the global oncology group in AstraZeneca. You will have the opportunity to impact an industry-leading portfolio of programs from early clinical development of novel therapeutics through to post-marketing opportunities that support approved targeted therapies!

Key Responsibilities and Accountabilities:

  • Supports the operation of the Translational Pathology UK group by assisting the leadership with delivery of our cancer biomarker portfolio goals. 
  • Manages the department’s purchasing and accounts to ensure team remains within annual budget allocation. 
  • Contributes to strategic planning and preparation of proposals and business cases. 
  • Coordinates the outsourcing of assays and managing contract workers, including contract pathologists. 
  • Manages the department’s laboratory information management system. 
  • Drafting and updating standard operating procedures, work instructions, scoring sheets. 
  • Maintains up to date laboratory staff and contractor training and proficiency records.
  • Manages and ensures the portfolio management system (Smartsheet) is up to date.
  • Designs and supports the implementation of improvements in scientific or operational approaches and technologies across area of responsibility to improve the quality, efficiency, and effectiveness of projects. 
  • Serves as a resource for others by sharing expertise, within and beyond the Translational Medicine and Cancer Biomarker Development departments, in own area of expertise, or defines and communicates important initiatives to own team. 
  • Collaborates with other functions, including R&D clinical pharmacology and safety science, early development, and drug discovery teams and ensures effective communication. 
  • Ensures own work, and work of team, is compliant with Good Clinical Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulation.
  • Acts as sample owner for the Translational Pathology group of commercial human biological tissue samples under the team's remit.  

Skills and experience:

  • Minimum of 2 years of pharmaceutical industry experience (or equivalent experience).
  • Experience in histology techniques or working with pathologists.
  • Experience in project management, including using project management software such as Asana, Smartsheet, and demonstrated track record of success in delivering projects on-time and on-budget.
  • Strong organizational skills, including good time management skills. Must be highly organized and able to work independently on multiple tasks in a fast-paced environment.
  • Takes appropriate initiative and accountability including proactively prioritizing work in alignment with business requirements.
  • Experience handling the outsourcing and management of outsourced projects.
  • Experienced in using MS Office Suite, especially PowerPoint, Word and Excel.
  • Strong interpersonal and communications skills.
  • Familiarity with human tissue tracking software or LIMS.

Desirable/Advantageous – Although training will be given, experience in the following areas would provide a distinct advantage.

  • PhD with exposure in a relevant field
  • Knowledge of immunohistochemistry (brightfield or fluorescence), microscopy and carrying out biomarker quantification studies using digital image analysis software.
  • Knowledge in one or more AZ portfolio areas: tumour drivers and resistance, DNA damage response (DDR), immuno-oncology (IO), antibody drug conjugates (ADC) and epigenetics
  • Some experience or exposure to microscopy and digital image analysis with software such as HALO or Visiopharm
  • Functional knowledge of FDA Code of Federal Regulations Title 21 Parts 50, 56, 312; Good Clinical Practice for Laboratories; any AZ processes and policies involved in relation to the acquisition, receipt, storage, use and disposal of human tissue samples. 
  • Familiarity with cell culture and interpreting Genomics and RNA sequencing data.

Locations: Cambridge UK

Salary: Competitive + Excellent Benefits 


Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

  • If you’re curious to know more then please reach out to Sophie Halpin.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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