The research group of Dr. Evgeny Zatulovskiy is recruiting a postdoctoral research associate in the area of Quantitative Cell Biology/Systems Biology.
We are an interdisciplinary research team interested in animal cell size regulation and decision making (https://www.zatulovskiylab.org). While different cell types in our body differ in size by many orders of magnitude, cells of a given type are incredibly uniform in size, suggesting that cell size is tightly controlled and crucial for tissue function. Consistent with this, significant cell size alterations are often associated with diseases and ageing. Nevertheless, surprisingly little is known about how size affects specific aspects of cell physiology, and we are only beginning to understand what molecular mechanisms regulate animal cell size. In the Zatulovskiy lab, we apply a systems biology approach and a diverse set of state-of-the-art quantitative techniques (including live-cell fluorescence microscopy, flow cytometry, SILAC proteomics, CRISPR/Cas9-mediated gene editing, and mathematical modeling) to solve a century-old puzzle of how animal cells regulate their size and how changes in cell size affect cell behaviours and fate decisions in health and disease.
Our group is part of the Department of Biochemistry at the University of Cambridge (https://www.bioc.cam.ac.uk/research/faculty/evgeny-zatulovskiy). The University of Cambridge provides a unique cultural and scientific environment, access to cutting-edge research facilities, and unlimited opportunities for collaboration.
We are looking for a highly motivated researcher interested in quantitative cell biology to work on one or more of the following projects:
-Investigating the roles of cell size deregulation in cancer cell proliferation, migration, and drug resistance
-Identifying the molecular mechanisms through which an increase in cell size promotes cellular ageing
-Exploring the effects of cell size on stem cell fate decisions.
A suitable candidate will have completed a PhD and demonstrated a high research impact and extensive experience in one or more of the following areas: quantitative cell biology, biochemistry, quantitative proteomics and mass spectrometry, stem cell biology, cancer biology, bioinformatics, system biology, biophysics, or other related fields.
In our group we strive to create an inclusive, friendly, and supportive atmosphere to ensure that all the trainees achieve their scientific and career goals. International applicants and applicants from underrepresented groups are highly encouraged to apply.
Please provide your CV, contact details of two academic references, and a brief statement describing your research experience, interests, and motivations for joining our group.
Fixed-term: The funds for this post are available from 15 January 2024 until 14 January 2029 in the first instance.
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