We are currently seeking a highly motivated and talented postdoctoral researcher in biomedical data science to join our team at the Cambridge Baker Systems Genomics Initiative (CBSGI) and Cardiovascular Epidemiology Unit (CEU) at the Department of Public Health and Primary Care (DPHPC). The post would suit a naturally collaborative, self-motivated researcher interested in the aetiology and prediction of cardiovascular and metabolic diseases as well as their common comorbidities. They will have experience in the application of machine learning, artificial intelligence, bioinformatics and biostatistics to analyse large-scale genomic and phenotypic data in the CEU's broad portfolio of multi-omic cohorts.
The primary role of the post holder will be to lead projects involving the quantitative analysis and interpretation of genomic and phenotypic data using polygenic scores, GWAS, Mendelian randomisation, and other statistical and machine-learning techniques. The successful role-holder will have research interests aligned with those of CBSGI and CEU. They will have the freedom to develop new research ideas, in particular by leading/contributing to new grant or fellowship applications.
Initial potential research projects include:
- developing polygenic scores that use the full spectrum of allele frequencies
- integrating multi-omics data to determine the molecular etiology of specific cardiometabolic multimorbidity patterns
- uncovering demography-based heterogeneity in causal effects of molecular traits on disease outcomes
- investigating rare high penetrance variants and downstream molecular and cellular aetiologies
This position is full time and is available for up to 2 years from commencement in post initially with the possibility of extension.
We offer an excellent employment package that includes:
- Pension schemes
- Hybrid working through a blend of remote and office working
- Family-friendly initiatives
- Career development opportunities
- Support for health & mental wellbeing
- Generous holiday entitlement
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
The post will be located at the new Victor Phillip Dahdaleh Heart & Lung Research Institute on the Cambridge Biomedical Campus, Papworth Road, Trumpington, Cambridge CB2 0BB
Informal enquiries can be made to Professor Michael Inouye (firstname.lastname@example.org)
Closing date: 5 December 2023
Interview Date: week commencing on the 11 December 2023
Appointment at Research Associate level is dependent on having a PhD (or equivalent experience), including those who have submitted but not yet received their PhD. Where a PhD has yet to be, awarded appointment will initially be made at research assistant and amended to research associate when the PhD is awarded (PhD needs to be awarded within 6 months of the start date).
Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Please quote reference RH38123 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.