Join our multi-skilled On Market Technical group at AstraZeneca, where we are dedicated to the technology transfer and lifecycle management of commercial active pharmaceutical ingredients (API). As a Senior Scientist, you will play a crucial role in ensuring robust technology transfer, validation, and manufacturing to maintain continuity of supply and ensure license to operate.
We also strive to continue to deliver business value through optimisation and redesign of manufacturing process and controls, alongside new supply chain design. AstraZeneca currently manufactures a high percentage of commercial API externally with CDMOs, however we are excited to be establishing a new launch facility in Dublin over the coming years. AstraZeneca have >60 commercial API.
As a Senior Scientist, you will be responsible for supporting the technical contribution to maintain and optimise supply for one or more AstraZeneca commercial products. You will identify, develop and implement process improvements for commercial products through the use of existing and cutting-edge technologies. You will also provide expert technical input to change control and improvement activities at CMOs and internal AZ API manufacturing sites. Your role will also involve authoring or providing a significant contribution to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product.
- BSc/PhD level education in a relevant discipline and experience working within a Research & Development or Manufacturing environment, within the pharmaceutical industry.
- Technical expertise and understanding of practical synthetic organic chemistry.
- A good understanding of the overall drug development process from discovery through to launch.
- Experience of technical supervision and leading small teams of people or scientific projects.
- A thorough understanding of the principles and management of SHE and cGMP.
- Experience of delivering CMC content or contributions to regulatory filings throughout the life cycle of process development, in the pharmaceutical industry.
At AstraZeneca, we are driven by our commitment to deliver accelerated growth and to make people's lives better. We are part of an inclusive and giving community, where we support and help each other on our journeys. We are disciplined thinkers and doers, thriving in our often intense and ambiguous environment, seeking out new challenges and working towards new solutions. If you have the passion and the drive to accelerate growth and make people's lives better, then this is the place for you.
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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.