These enzymes can efficiently activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids, respectively, through a mode of activation that has never been observed in nature. These intermediates can react with a variety of substrates such as olefins, N-H bonds, C-H bonds, and sulfides, offering great synthetic utility, as for example in the synthesis of chiral cyclopropanes and sulfimides.
The screening kit contains 32 enzymes that were engineered in the laboratory of Prof. Frances Arnold, at Caltech. Provivi obtained a worldwide exclusive license to this technology. The kit will be available through Strem so that researchers are able to quickly screen a small number of diverse biocatalysts to pick the best solution.
About the Kit
The Kit (Strem Catalog No. 96-1580 Provivi Carbene/Nitrene Transferase Screening Kit) contains 32 Provivi enzymes.
www.strem.com/catalog/v/96-1580/provivi_carbene_nitrene_transferase_screening_kit
Strem ChemicalsUK Ltd, a local company has been providing support supportto research in Cambridgeshire for the past 22 years, supplying specialty chemicals of high purity. Strem’s key products include catalysts, ligands, organometallics, metal carbonyls and nanomaterials. Its products are used for research and development and commercial scale applications, especially in the pharmaceutical, microelectronics, chemicals and petrochemicals industries. Strem Chemicals also provides custom synthesis, process development and cGMP manufacturing services.
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For more information visit www.strem.com email us on enquiries@strem.co.uk or phone us on 01223 873028
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