Strem Chemicals UK offers advanced CTAB free gold nanorods for Life Sciences


15-11-2016

Stable, non-toxic gold nanorods lead to much improved biomedical treatment methodologies, as well as a host of other in-vivo applications.

Add This Share Buttons

In recent years, biocompatible nanostructured materials have emerged as promising delivery systems for anticancer drugs, DNA and imaging agents. Specifically, colloidal gold nanoparticles (GNPs) with their fine tunable optical and electrical properties, allow implementations in cancer diagnosis and photothermal therapy.  GNPs are able to convert adsorbed light into localized thermal energy via surface plasmon resonance mechanism and ablates targeted solid tumors [1-2].

Conventional spherical GNPs display wavelength adsorption between 500-550 nm which is insufficient for tissue penetration. However, gold nanorods (GNRs), due to the morphological aspect ratio, show near-IR absorbing properties from about 700 to 800 nm which boosts their value in photothermal cancer therapy [2].

The most common synthetic method of GNRs involves cetyltrimethylammonium bromide (CTAB) for colloidal stabilization.  This material is a major barrier in the application of GNR-based materials, especially for in-vivo applications. CTAB is a cytotoxic material which is why its removal from the particle surface is one of the primary challenges. It is believed that complete removal of CTAB from GNRs will ultimately lead to the best cell viability of the GNRs [3-4].

In collaboration with SONA Nanotech, Strem Chemicals presents CTAB free GNRs designed for life sciences and specifically in-vivo human applications:

 

Catalog #

Name

Axial Diameter

Wavelength

79-7010

Gold Gemini Nanorods; CTAB Free

13-18 nm

650 nm

79-7015

Gold Gemini Nanorods; CTAB Free

13-18 nm

700 nm

79-7020

Gold Gemini Nanorods; CTAB Free

10-13 nm

750 nm

79-7025

Gold Gemini Nanorods; CTAB Free

10-13 nm

800 nm

79-7030

Gold Gemini Nanorods; CTAB Free

9-12 nm

850 nm

 

GNRs, with tunable electro-optical properties and controlled with minimum amount of surfactants, allow their application not only for certain biomedical properties, but also for colorimetric and fluorescent detections, imaging macrophage activity, electrochemical gas sensing/biosensing and catalytic application [5-7]. Strem Chemicals also offers ascorbic acid and CTAB stabilized gold nanorods:

Catalog #

Name

Axial Diameter

Wavelength

79-0136

Gold Nanorods; contains CTAB

Aspect Ratio: 3-3.5

680 nm

79-6000

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

25 nm

550 nm

79-6005

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

25 nm

600 nm

79-6010

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

25 nm

650 nm

79-6015

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

25 nm

700 nm

79-6020

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

10 nm

700 nm

79-6025

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

10 nm

750 nm

79-6030

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

10 nm

780 nm

79-6035

Gold Nanorods; < 0.1% ascorbic acid, < 0.1% CTAB

10 nm

808 nm

 

In addition, Strem Chemicals offers three different gold nanorod kits.

Catalog #

Name

96-1549

Gold Gemini Nanorods Kit, CTAB Free (Wavelength 650-850 nm)

96-1530

Gold Nanorods Kit (Axial Diameter - 25 nm, wavelength 550-700 nm)

96-1535

Gold Nanorods Kit (Axial Diameter - 10 nm, wavelength 700-808 nm)

 

References:

  1. E. Carrasco et al. Adv. Funct. Mater. 2015, 25, 615-626
  2. Lakhani et al, Nanotechnology 26 (2015) 432001 and references are therein
  3. C. Kinnear et al. Angew. Chem. Intern. Ed., 2014, 53, 12613-12617.
  4. L. Vigderman et al.Angew. Chem. Int. Ed. 2012, 51, 636-641.
  5. J. Olson et al. Chem. Soc. Rev., 2015, 44, 40-57
  6. M Baaske et al; Nature Nanotechnology, 2014, 9, 933-939
  7. Bo et al, ACS Nano, 2013, 7, 5993-6000

 

Visit the below link to view additional details on our website: Gold Nanorods Synthesized without CTAB

___________________________________________

 

 

To read more information, click here.

For over twenty-five years, Strem Chemicals UK has been distributing high quality specialty chemicals, from Strem Chemicals, Inc, in the UK and Ireland. Strem products are used for research and development and commercial scale applications, especially in the pharmaceutical, microelectronics, chemicals and petrochemicals industries.

Strem Chemicals UK Ltd