Redefining drug discovery with NAMs: Medicilon’s AI-driven NAMs platform

In April 2025, the US FDA began phasing out mandatory animal testing for monoclonal antibodies and biologic drugs, a landmark decision that officially brings New Approach Methodologies (NAMs) into the global R&D spotlight.

AI-Driven NAMs Platform

At Medicilon, we’re proud to be at the forefront of this transformation. Our NAMs Drug R&D Service Platform integrates AI-driven modelling, advanced in vitro systems, and dry-wet integration to accelerate discovery, improve prediction accuracy, and meet evolving regulatory expectations.

What makes our NAMs platform unique: 

  • AI-assisted drug discovery: From target identification to hit-to-lead and lead optimisation. 

  • In vitro safety assessment: Cardio-, hepato, and nephrotoxicity, cytokine release, immunotoxicity, and more. 

  • PDXO biobank and organoid models: Human-relevant systems for efficacy and safety evaluation. 

  • PBPK modelling: Predicting human pharmacokinetics from preclinical data. 

With NAMs, we’re reducing reliance on animal studies while increasing human relevance, efficiency, and sustainability in drug R&D. 

Let’s connect or reach out directly: 
Email: [email protected] Tel: +44 1223981791  
Global Headquarters: 585 Chuanda Road, Pudong, Shanghai, 201299, China  
UK Office: Ailla Future Business Centre, King's Hedges Road, Cambridge, CB4 2HY 



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