Naïve, primed or somewhere in between?
Single cell analysis reveals details of heterogeneity in stem cell populations and how naive cells become primed for differentiation. Research also identified a new intermediate cell population showing characteristics of naïve and primed human embryonic stem cells which might be present in the early human embryo.
How lung tissue forms immune cell hubs in times of need
Immunology researchers at the Babraham Institute have uncovered how lung tissue is remodelled to support an immune response to influenza. If the research findings can be applied to the development of the seasonal influenza vaccination, the result would be more robust protection against multiple influenza strains. Findings are also relevant to understanding a variety of autoimmune diseases and the…
Kick-starting the genome in early development
We can think of the egg and sperm as information capsules with stored instructions for starting a new life, but post fertilisation, what kick starts the interpretation of these instructions?
Babraham Institute steps-up equality, diversity & inclusion commitments
The Institute is delighted to have joined both the Equality, Diversity and Inclusion in Science and Health (EDIS) coalition and the Stonewall Diversity Champions programme for embedding LGBT inclusion.
What can worms tell us about human ageing?
Community-developed blueprint of worm metabolism holds promise for greater understanding of ageing.
Wolf Reik awarded Wellcome Trust Investigator Award
Professor Wolf Reik, Associate Director and Head of the Epigenetics research programme at the Babraham Institute has been awarded a Wellcome Trust Investigator Award for research into how to reprogramme the epigenome. The Award provides £2.6 million in funding for five years. Research funded by the award will commence in October this year and involve the recruitment of three new research…
Placenta defects key factor in prenatal deaths
The role of the placenta in healthy fetal development is being seriously under-appreciated, according to a new paper published last week.
Genes for age-linked brain deterioration identified
A group of genes and genetic switches involved in age-related brain deterioration have been identified by scientists at the Babraham Institute, Cambridge and Sapienza University, Rome.
Reik Lab part of team shortlisted for Cancer Research UK’s Grand Challenge Award
A multi-disciplinary team of scientists, including Professor Wolf Reik from the Babraham Institute, has been shortlisted to the final stages of Cancer Research UK's Grand Challenge* – an ambitious series of £20m global grants tackling some of the toughest questions in cancer research.
New fundamental biology may aid cancer treatments
New research represents a promising step towards better understanding of a key cancer gene.
Cannibal cells may limit cancer growth
Cell cannibalism in tumour samples has been observed for over a century, yet this unusual behaviour is not well studied.
Genetic DJ: Growing cells remix their genes
Moving genes about could help cells to respond to change according to scientists at the Babraham Institute in Cambridge, UK and the Weizmann Institute, Israel.
Researchers identify missing links that connect human DNA variation with disease
A team of Cambridge researchers led by scientists at the Babraham Institute have discovered the hidden connections in our genomes that contribute to common diseases.
Vitamins A and C help erase cell memory
Vitamins A and C aren’t just good for your health, they affect your DNA too.
Insights into the development of sperm and egg cell precursors in the embryo
A bit like someone looking into a mirror reflected in another mirror, as one new life is developing as an embryo, the capacity to produce the next generation of life is already being established in that embryo.
Countdown to the Immune Army at Royal Society Summer Science Exhibition
The Babraham Institute's Immune Army and team of volunteers land at the Royal Society Summer Science Exhibition 2015 in London next week.
Award boosts knowledge exchange and commercialisation at Babraham Institute
A BBSRC award to the Babraham Institute will enhance the Institute’s knowledge exchange and commercialisation (KEC) programme to disseminate the results of the Institute’s world-class research and build links with industry.
PharmML opens new opportunities for drug discovery research
A novel format for exchanging computational models in pharmaceutical R&D, PharmML (Pharmacometrics Markup Language), opens new opportunities for collaborations in drug discovery research.
New technique has implications in determining the genetic basis of thousands of diseases
Researchers at the Babraham Institute and the Francis Crick Institute have developed and used a new technique to join the dots in the genomic puzzle.
Babraham Institute gains Silver Athena SWAN Award
The Babraham Institute has received a Silver Athena SWAN award following a successful first application submitted in November last year.
Molecular exploration at the Science Festival
The Babraham Institute created a bit of a stir at the Cambridge Science Festival on the weekend 14-15 March. Thanks to the launch of a new 'Molecular Explorers' exhibit, visitors flocked round the exhibit to learn more about the Institute's scientific activities and embark on a journey of molecular discovery.
Research aids understanding of cellular ageing
Researchers at the BBSRC-supported Babraham Institute have mapped the physical structure of the nuclear landscape in unprecedented detail to understand changes in genomic interactions occurring in cell senescence and ageing.
Babraham Institute hosts Newton International Fellow
A fellowship to host Dr Wim Pierson at the Babraham Institute is one of the Newton International Fellowships announced yesterday. The Newton International Fellowships are awarded jointly by two of the UK’s national research academies – the British Academy and the Royal Society.
Babraham Institute researchers put UTC students through their protein paces
Sixty Year 12 students from Cambridge’s University Technical College have started a bespoke six week project developed by Babraham Institute scientists and based around research at the Institute. The Institute is one of the University Technical College (UTC) Cambridge sponsors.