MedTech
Allostery under the lens of molecular dynamics simulations
On Wednesday 26th April 2023, we sponsored a virtual session hosted by the Boston Area Group for Informatics and Modeling (BAGIM) and their equivalent group in San Diego, SAGIM. Professor Julien Michel, Professor of Biomolecular Simulation at The University of Edinburgh and member of C...
D-CYPHR goes live across the UK
Largest ever DNA and health research programme for children and young people launches to tackle toughest health challenges – through the power of spit. ...
Looking 'under the hood': using pyflare to streamline hit identification
Background Assessing the binding potency of millions of different compounds against a common protein target presents many challenges in a wet laboratory. Even with advanced lab robotics and automation platforms, wet laboratory high-throughput screening (HTS) is still hindered by time, ...
Orientate your proteins on ligand superimposition using the Flare™ Python API
The importance of protein and ligand orientation during 3D visualization The orientation of protein structures is a simple yet essential manipulation in any 3D visualization tool for medicinal and computational chemists. In silico workflows during early-stage hit and lead identificatio...
Using molecular dynamics to produce an ensemble of protein conformations for more biologically relevant docking experiments
Introductory Overview Earlier today, our Application Scientists, Abhijit Kayal and Ryuichiro Hara, led an exclusive online webinar session, focused on demonstrating how Molecular Dynamics and docking can work in synergy as an advanced research technique. ...
Identify the most active chemical structures with key desired properties through R-group decomposition and analysis
Drug discovery research often involves making small modifications to a compound and studying the subsequent effect on activity. Once a closely related series of compounds has been made and tested, it is very important to analyze which of the substituents enhances activity, and to also k...
CMR Surgical ramps up virtual reality offering in world first VR simulator training
Versius® becomes the first soft-tissue surgical robotic system to feature a headset-based virtual reality simulator as part of its metrics-based training pathway ...
Qkine announces collaboration with Sartorius
Qkine, a manufacturer of animal-free, highly bioactive, and innovative proteins, announces its collaboration with Sartorius, a global life science group, to supply growth factors and cytokines for stem cell and organoid research, as part of a comprehensive workflow solution. ...
Qureight collaborates with AstraZeneca on lung disease research
Cambridge-based data analytics company Qureight has entered into a multi-year collaboration with biopharmaceutical company AstraZeneca. ...
Cambridge Filmworks share Genomics England: Owen’s Story
Owen lives with a rare genetic thyroid condition. In this new film from Cambridge Filmworks, Owen’s parents Sarah and Rob share how life has changed for their family in the nearly 5 years since the diagnosis through whole genome sequencing and the 100,000 Genomes Project. ...