25 species revealed for 25 Genomes Project
To commemorate the Wellcome Trust Sanger Institute turning 25 in 2018, the Institute and its collaborators* are sequencing 25 new genomes of species in the UK**.
The Sanger Institute introduces its new Laboratory Technician Apprentice
A new Laboratory Technician Apprentice, Claire Cormie, has joined the Wellcome Trust Sanger Institute.
Wellcome Genome Campus Conference Centre boosts its offering for event organisers
The Wellcome Genome Campus Conference Centre in Hinxton, Cambridge, has launched a new initiative aimed at event organisers, offering a comprehensive range of services designed to support those holding meetings and conferences at the Conference Centre.
New tool allows analysis of single-cell RNA data in pre-malignant tumours
Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that was able to show, for the first time, which genes were expressed by individual cells in different genetic versions of a benign blood cancer.
Scientists and conservation charities join forces to track Spanish bluebell invasion
The Wellcome Genome Campus Public Engagement team has joined forces with the Eden Project and The Wildlife Trust for Bedfordshire, Cambridgeshire and Northamptonshire to launch the first ‘Bluebell Barcoding Day’ today (Wednesday 6 April), which will help track the threat to English bluebells from an invasive Spanish variety.
Strongest single gene conclusively implicated in schizophrenia
An international consortium of researchers, led by a team at the Wellcome Trust Sanger Institute, has discovered conclusive evidence for the involvement of a gene called SETD1A in schizophrenia. Damaging changes to this gene, which occur rarely, increase the risk of schizophrenia 35-fold and also increase risk for a wide range of neurodevelopmental disorders.
Wellcome Genome Campus launches new BioData Innovation Centre
The Wellcome Genome Campus has an exciting development lined up for this year. In 2016 the campus will open the doors on its brand new BioData Innovation Centre, an outstanding new home for innovative genomics and biodata companies.
Genomic sequencing reveals link between STIs and leading cause of infectious blindness
For the first time, genome sequencing has been carried out on Chlamydia trachomatis (C. trachomatis), a bacteria responsible for the disease Trachoma - the world’s leading infectious cause of blindness, according to a study in Nature Communications.
Move over Alan Sugar...the Sanger Institute introduces its apprentices
Last week, two IT Apprentices joined the Wellcome Trust Sanger Institute – Dane Ebanks and Tom Ashcroft.
Inflammatory bowel disease (IBD) genetically similar in Europeans and non-Europeans
The first genetic study of inflammatory bowel disease (IBD) to include individuals from diverse populations has shown that the regions of the genome underlying the disease are consistent around the world.
Host-targeted antibodies effective against malaria
All antimalarial drugs produced to date target the disease-causing parasite, but a new study in the Journal of Experimental Medicine shows that drugs which target host proteins are also a potential avenue for new interventions.
Genome of emerging antibiotic resistant bacteria decoded
An analysis of the largest genetically decoded collection of the bacterial pathogen Klebsiella pneumoniae, which causes a spectrum of diseases in humans and animals, reveals the impact of antibiotic treatment on its population structure and provides the tools needed to track this important pathogen.
Global Alliance for Genomics and Health marks two years of progress
The Global Alliance for Genomics and Health (GA4GH), an international coalition dedicated to improving human health by maximising the potential of genomic medicine, marked its second anniversary this month. Today, more than 250 GA4GH Members are coming together in the Netherlands to collaborate on the development of innovative, integrated solutions that promote genomic and clinical data sharing,…
Healthy skin helps identify cancer’s origins
Normal skin contains an unexpectedly high number of cancer-associated mutations, according to a study published in Science. The findings illuminate the first steps cells take towards becoming a cancer and demonstrate the value of analysing normal tissue to learn more about the origins of the disease.
Antibiotic resistant typhoid detected in countries around the world
Unappreciated global spread of multiple antimicrobial resistant typhoid mapped by international consortium
Most people eager to know the secrets of their genetics
A survey of nearly 7000 people has revealed that 98 per cent want to be informed if researchers using their genetic data stumble upon indicators of a serious preventable or treatable disease. The study, which comes after the Government’s announcement that Genomics England will sequence 100,000 genomes by 2017, begins an important and on-going conversation about how our genomic data is used.
Single cells seen in unprecedented detail
Researchers have developed a large-scale sequencing technique called Genome and Transcriptome Sequencing (G&T-seq) that reveals, simultaneously, the unique genome sequence of a single cell and the activity of genes within that single cell.
Mountain gorillas enter the genomic age
The first project to sequence whole genomes from mountain gorillas has given scientists and conservationists new insight into the impact of population decline on these critically endangered apes.
Brain-dwelling worm in UK man’s head sequenced
For the first time, the genome of a rarely seen tapeworm has been sequenced. The genetic information of this invasive parasite, which lived for four years in a UK resident’s brain, offers new opportunities to diagnose and treat this invasive parasite.
Large-scale study raises hopes for development of E. coli vaccine
The largest ever study of the bacterium enterotoxigenic Escherichia coli (ETEC) has raised hopes that a global vaccine can be developed. This bacterium causes 400 thousand deaths and 400 million cases of diarrhoea each year in low-and-middle-income countries as well as misery to many travellers to these regions.
Global Alliance for Genomics and Health members meet to advance genomic data sharing
The Global Alliance for Genomics and Health convened its second major meeting of 2014 yesterday (Monday), bringing together more than 250 international leaders to collaborate on the development of innovative solutions to accelerate sharing of genomic and clinical data.
Sanger Institute researcher collaborates on story of love and flu
A radio drama about love and flu produced in collaboration with Professor Paul Kellam, a member of Faculty at the Wellcome Trust Sanger Institute, starts on Radio 4 next Monday (27 October).
Gene variant dramatically reduces ‘bad’ lipids
Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. The study is the first to emerge from the UK10K Project’s cohort of samples from the general public and demonstrates the power of whole genome sequencing at scale.
Genome-wide association study in disease-causing bacteria paves way for clinical tool
Researchers have developed a powerful new tool to identify genetic changes in disease-causing bacteria that are responsible for antibiotic resistance. The results from this technique could be used in clinics within the next decade to decide on the most effective treatments for diseases such as pneumonia and meningitis.
New malaria vaccine candidates identified
Researchers have discovered new vaccine targets that could help in the battle against malaria. Taking a new, large-scale approach to this search, researchers tested a library of proteins from the Plasmodium falciparum parasite with antibodies produced by the immune systems of a group of infected children.