Healthcare and Life Science
Why VHHs Are Attractive Targeting Ligands for AOCs
The success of an antibody-oligonucleotide conjugate rests as much on the targeting ligand as on the payload it carries. This blog walks through the four-step AOC mechanism, from receptor binding and internalisation through payload release and biological activity, and highlights endosom...
Accelerating VHH-Enabled AOC Discovery
Antibody-oligonucleotide conjugates depend on targeting ligands that combine specificity, internalisation and developability with conjugation compatibility, a harder bar than target identification alone. This blog sets out how Isogenica's synthetic VHH platform supports AOC discovery: u...
Tagomics introduces LiquiPath, a first-in-class cfDNA-based blood test for multi-organ drug safety monitoring
Non-invasive cell-free DNA liquid biopsy platform for multi-organ monitoring of drug-safety across preclinical and clinical settings Early access programme now open for drug developers to shape future platform capabilities and applicationsNew brand identity and website mark the exp...
Guardtech accelerate Automotive cleanroom provision to ensure clients stay in pole position
The contamination control specialists' adaptable portfolio is helping everyone from Formula One innovators to automotive manufacturers and advanced spray finishing applications find the perfect cleanroom solution ...
Inspirational East Anglian Air Ambulance patient to take on Trek 24 Cambridgeshire to support crew who saved his life
Pedro Santos will tackle 2.4-mile circuit in his wheelchair alongside friends A man whose life changed forever after a serious road traffic collision is taking on East Anglian Air Ambulance's Trek 24 Cambridgeshire this September to give something back to the charity whose specialist t...
SynGenSys introduces expanded CHO.SET synthetic promoter library for enhanced biomanufacturing
· CHO.SET® 2.0 library of synthetic promoters provide tuneable expression of transgenes whilst maximising CHO cell productivity· CHO.SET® promoters enable higher protein titres, reduced costs and shorter devel...
CN Bio awarded Innovate UK grant to reduce animal use in pharmacokinetic studies
Grant funding delivered in partnership with the NC3Rs, in support of UK Government roadmap to reduce animal testing by 2030 Project to develop standardized workflow to more accurately predict drug behaviors, reduce animal testing and streamline development of safer, more effective ...
Milner Therapeutics Institute supports new £20 million MRC Hub to accelerate next-generation drug discovery
The Milner Therapeutics Institute (MTI) is proud to be part of a new £20 million Medical Research Council (MRC) investment that will establish a UK Pre-clinical Translational Models Hub. ...
Andrew Glover succeeds Stuart Evans as Chair of Caring Together Charity
Cambridge-based Andrew Glover (left in the photo) has been appointed as the new Chair of the Board of Trustees at Caring Together Charity, bringing with him extensive experience in business leadership and personal insight into the realities of caring. ...
Welbeck Cambridge reaches major development milestones as opening preparations accelerate
Welbeck Health Partners has announced significant progress in the development of its new Welbeck Cambridge facility, with major construction milestones achieved and operational planning continuing ahead of the centre's opening. ...