Cresset
Computational solutions for drug discovery
Cresset® is leading the digital revolution in molecule design and cross-team communication. We combine cutting-edge science with AI/ML to enable our customers to advance human health by discovering new compounds faster and more efficiently. Built from 20 years of computational chemistry innovation from working directly on customer problems, we provide an unrivalled platform for discovery organizations to achieve scientific success.
Our intuitive in silico CADD software programs combine unique ligand-based and structure-based computational methods, while the Torx® DMTA cloud application facilitates secure, real-time collaboration between chemistry teams, CROs and external partners. Our Discovery CRO services provide customers with tailored molecular modeling solutions, the latest techniques and custom integration to advance their projects, while creating, broadening and protecting IP.
By harnessing digital transformation to accelerate communication across the workflow, Cresset’s trusted, pioneering solutions empower organizations to make quicker, more informed decisions and design the molecules that matter.
Products and services
Flare™ ligand-based and structure-based drug design
A single platform for ligand-based and structure-based drug design that enables research chemists to discover novel small molecules more efficiently and effectively.
Blaze™: Effective ligand based virtual screening
Effective ligand based virtual screening
Dramatically increase your wet screening hit rate at a fraction of the cost with a biologically intelligent search of chemical databases.
Blaze uses the shape and electrostatic character of known ligands to rapidly search large chemical collections for molecules with similar properties. It is excellent for replacing peptides with non-peptides and steroids with non-steroids, as well as finding novel leads from screening hits or known drug structures.
Spark
Discover new directions for your project using bioisosteres
Spark is an exciting and powerful way of generating novel and diverse structures for your project. Spark uses Cresset’s field technology to find biologically equivalent replacements for key moieties in your molecule, enabling you to find new structures in new chemical space.
Use Spark to optimize your leads and improve your IP position, or to switch scaffolds completely while retaining activity and minimizing ADME and toxicity issues.
