Nanotechnology takes on diabetes

A sensor which can be used to screen for diabetes in resource-poor settings has been developed by researchers and tested in diabetic patients, and will soon be field tested in sub-Saharan Africa.

These sensors can be used to screen for diabetes in resource-poor countries, where disposable test strips and other equipment are simply not affordable
- Ali Yetisen

A low-cost, reusable sensor which uses nanotechnology to screen for and monitor diabetes and other conditions, has been developed by an interdisciplinary team of researchers from the University of Cambridge, for use both in clinics and home settings.

The sensors use nanotechnology to monitor levels of glucose, lactate and fructose in individuals with diabetes or urinary tract infections, and change colour when levels reach a certain concentration. They can be used to test compounds in samples such as urine, blood, saliva or tear fluid.

Earlier this year, clinical trials of the sensors were carried out at Addenbrooke’s Hospital to monitor glucose levels in 33 diabetic patients. Recently, the team has also partnered with a non-governmental organisation to deploy the technology for field use in Ghana early next year.

According to the International Diabetes Federation, there are an estimated 175 million undiagnosed diabetic patients worldwide, 80% of whom live in low- and middle- income countries. Development of non-invasive and accurate diagnostics that are easily manufactured, robust and reusable will allow for simple monitoring of high-risk individuals in any environment, particularly in the developing world.

The sensors developed by the Cambridge team are made using laser light, which organises metal nanoparticles into alternating layers in thin gel films to produce the sensors in a matter of seconds.


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Image: Diabetes 1/4
Credit: Dennis Skley via Flickr


Reproduced courtesy of the University of Cambridge
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