Punctured lung affects almost one in 100 hospitalised COVID-19 patients


11-09-2020
plastic 'lung' balloon with a sticking plaster - illustration:   X is for X-ray  Credit: Carol VanHook

As many as one in 100 patients admitted to hospital with COVID-19 develop a pneumothorax – a ‘punctured lung’ – according to a study led by Cambridge researchers.

Like the inner tube of bicycle or car tyre, damage to the lungs can lead to a puncture. As air leaks out, it builds up in the cavity between the lung and chest wall, causing the lung to collapse. Known as a pneumothorax, this condition typically affects very tall young men or older patients with severe underlying lung disease.

During the pandemic, a team at the University of Cambridge and Addenbrooke’s Hospital, Cambridge University NHS Foundation Trust, observed several patients with COVID-19 who had developed punctured lungs, even though they did not fall into either of these two categories.

“We started to see patients affected by a punctured lung, even among those who were not put on a ventilator,” says Professor Stefan Marciniak from the Cambridge Institute for Medical Research. “To see if this was a real association, I put a call out to respiratory colleagues across the UK via Twitter. The response was dramatic – this was clearly something that others in the field were seeing.”

Professor Marciniak subsequently obtained the appropriate ethical approvals and exchanged anonymised clinic information about 71 patients from around the UK. This led to a study published in the European Respiratory Journal.

Although the team are unable to provide an accurate estimate of the incidence of punctured lung in COVID-19, admissions data from the 16 hospitals participating in the study revealed an incidence of 0.91%.

“Doctors need to be alert to the possibility of a punctured lung in patients with COVID-19, even in people who would not be thought to be typical at-risk patients,” said Professor Marciniak, who is also a Fellow at St Catharine’s College, Cambridge. “Many of the cases we reported were found incidentally – that is, their doctor had not suspected a punctured lung and the diagnosis was made by chance.”

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Image: X is for X-ray

Credit: Carol VanHook

Reproduced courtesy of the University of Cambridge

 

The University of Cambridge is acknowledged as one of the world's leading higher education and research institutions. The University was instrumental in the formation of the Cambridge Network and its Vice- Chancellor, Professor Stephen Toope, is also the President of the Cambridge Network.

University of Cambridge (cam.ac.uk)