A postdoctoral Research Associate position is available to join the research group of Prof. Anna Philpott in the Wellcome-MRC Cambridge Stem Cell Institute, a world-leading centre for stem cell research (https://www.stemcells.cam.ac.uk/). The Philpott lab has broad interests in understanding the fundamental mechanisms that determine cell fate choice and differentiation during development, reprogramming and cancer. Establishing and maintaining the correct cell identity is fundamental for health. Understanding these mechanisms underpins successful reprogramming for disease modelling and may help to advance regenerative and cancer therapies.
The successful candidate will undertake a project investigating the transcriptional regulation of lineage fidelity during fate specification and differentiation of mouse embryonic stem cells, focusing on uncovering epigenetic and co-factor-dependent mechanisms underlying these processes. Within the laboratory, we use several experimental systems including mammalian embryonic stem cells, cancer cell culture, as well as Xenopus frog embryos. We use many techniques including genome-wide analysis of gene expression in single and multiple cells, chromatin binding and accessibility studies and CRISPR genome editing, alongside diverse biochemical approaches.
The successful candidate will have a PhD, experience in stem cell biology, developmental biology, or transcriptional regulation, and a proven track record in scientific publication. Prior experience in mammalian stem cell culture and in genome-wide transcriptional analysis are essential. Applicants must display an ability to undertake project management, work within a multi-disciplinary team environment, have good presentation and communication skills and the ability to contribute to an environment supporting researchers at all stages of their careers.
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Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
The closing date for applications is Tuesday 25 August 2026
The interview date for the role is to be confirmed
Please quote reference PS50705 on your application and in any correspondence about this vacancy.
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