The versatile cucurbituril kit is now available from Strem Chemicals

Strem offers a very versatile cucurbituril kit (96-7054) containing five key representatives of this family of container molecules. These macrocyclic molecules are comprised of two carbonyl domains and adopt the shape of containers and are assembled by a straightforward acid-catalyzed condensation reaction.

 

These very versatile compounds have been used as sites for chemical reactions performed in constrained environments which provide local high concentration of reagents and therefore lead to faster reaction kinetics and have the potential of leading to unexpected regio- and chemo-selectivities.

They have also been used as sensors for organic amines in view of functional groups present in the cucurbituril core structure. In this context they can be viewed as natural models for receptors of biologically relevant molecules and have been used to this end. Direct functionalization of the cucurbituril core can easily generate custom-made derivatives. Supramolecular architectures can and have therefore been constructed based on this core motif. They have proven quite useful as motifs in supramolecular chemistry.

Applications include:

  • Chambers for chemical reactions
  • Sensors for organic amines
  • Utility in the reduction of pollutions
  •  Laser dye applications
  • Molecular machines
  • Gene and drug delivery vehicles
  • Useful for bio-related applications, such as ion channel, enzyme assay, protein chips and selective protein isolation

For further information please contact us on 01223 373028 or enquiries@strem.co.uk

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