Healthcare and Life Science
Hidden drivers of aggressive childhood cancer revealed
New clues have been uncovered about why the childhood cancer, rhabdomyosarcoma, may behave aggressively. ...
Victory in sight in battle against blood virus
Clinicians from a specialist treatment hub at Addenbrooke’s Hospital believe the region is “on the home straight” in eradicating hepatitis C (HCV/HepC), a dangerous virus that attacks the liver. ...
Laura Tull shortlisted for Leader in Health & Safety Consultancy Award 2026
SHE does safety Director Laura Tull has been shortlisted for the Leader in Health & Safety Consultancy Award 2026, recognising an approach to consultancy built around practical, proportionate and genuinely useful health and safety support. ...
Qureight expands with addition of second site, to accommodate rapid growth and ongoing development of chest Foundation Model
Investment in new premises in London reflects significant milestone in Company’s growth, following $20 million Series B financingSupports rapid scale-up and development of foundational AI imaging model, to improve clinical trial design across broader range of chest diseasesCambridge, UK...
Why Antibody-Oligonucleotide Conjugates Are Gaining Momentum
Therapeutic oligonucleotides offer sequence-selective, programmable ways to modulate disease biology, but reaching the right cells outside the liver remains a persistent barrier. This blog introduces AOCs as a strategy for extending targeted delivery to skeletal muscle, heart and brain,...
How Are AOCs Being Applied?
AOCs are moving into clinical development across a growing range of therapeutic areas, from neuromuscular and rare genetic disease to CNS disorders and immuno-oncology. This blog reviews named clinical programmes, including Avidity's TfR1-targeting siRNA conjugate in myotonic dystrophy ...
Why VHHs Are Attractive Targeting Ligands for AOCs
The success of an antibody-oligonucleotide conjugate rests as much on the targeting ligand as on the payload it carries. This blog walks through the four-step AOC mechanism, from receptor binding and internalisation through payload release and biological activity, and highlights endosom...
Accelerating VHH-Enabled AOC Discovery
Antibody-oligonucleotide conjugates depend on targeting ligands that combine specificity, internalisation and developability with conjugation compatibility, a harder bar than target identification alone. This blog sets out how Isogenica's synthetic VHH platform supports AOC discovery: u...
Tagomics introduces LiquiPath, a first-in-class cfDNA-based blood test for multi-organ drug safety monitoring
Non-invasive cell-free DNA liquid biopsy platform for multi-organ monitoring of drug-safety across preclinical and clinical settings Early access programme now open for drug developers to shape future platform capabilities and applicationsNew brand identity and website mark the exp...
Guardtech accelerate Automotive cleanroom provision to ensure clients stay in pole position
The contamination control specialists' adaptable portfolio is helping everyone from Formula One innovators to automotive manufacturers and advanced spray finishing applications find the perfect cleanroom solution ...